RORgammat Inverse agonist 10 is a potent and orally bioavailable RORgammat (retinoic acid receptor-related orphan nuclear receptor gamma t) inverse agonist, with an IC50 of 51 nM. RORgammat is a major transcription factor of genes related to psoriasis pathogenesis such as IL-17A, IL-22, and IL-23R[1]
Molecular Weight:
572.50
Purity:
99.13
CAS Number:
[2413986-35-1]
Formula:
C25H26F6N6O3
Target:
ROR
Application Notes:
MCE Product type: Reference compound
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