MI-1063 is an inhibitor for DMD-2, that blocks the MDM2-p53 interaction, and activates the tumor suppressor function of p53. MI-1063 inhibits the growth of cancer cell RS4-11 and MV4-11 with IC50 of 179 nM and 93 nM. MI-1063 can be used as target protein ligand in synthesis of PROTAC degrader MD-265 (HY-169327)[1].
Molecular Weight:
588.50
CAS Number:
[1410737-39-1]
Formula:
C30H32Cl2FN3O4
Target:
Ligands for Target Protein for PROTAC,MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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