Fumarranol, a Fumagillin (HY-B0751) analogue, is a selective type 2 methionine aminopeptidase (MetAP2) inhibitor with a human IC50 of 3.2 µM. Fumarranol inhibits proliferation of bovine aortic endothelial cells and inhibits angiogenesis in a mouse matrigel plug model. Fumarranol can be used for the researches of cancer, diabetic retinopathy, age-related macular degeneration[1].
Molecular Weight:
280.36
CAS Number:
[912569-37-0]
Formula:
C16H24O4
Target:
MetAP
Application Notes:
MCE Product type: Reference compound
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