(R)-Benpyrine is the isomer of Benpyrine (HY-133807), and can be used as an experimental control. Benpyrine is a highly specific and orally active TNF-alpha inhibitor with a KD value of 82.1 µM. Benpyrine tightly binds to TNF-alpha and blocks its interaction with TNFR1, with an IC50 value of 0.109 µM. Benpyrine has the potential for TNF-alpha mediated inflammatory and autoimmune disease research[1].
Molecular Weight:
308.34
Purity:
99.17
CAS Number:
[2637243-08-2]
Formula:
C16H16N6O
Target:
TNF Receptor
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted