Zofenoprilat is an orally active inhibitor for angiotensin converting enzyme (ACE) with an IC50 of 1.7 nM. Zofenoprilat inhibits the expression of angiotensin II, reduces the blood pressure, exhibits thus cardioprotective and renalprotective activity. Zofenoprilat promotes the NO production, decreases endothelin-1 (ET-1) expression, exhibits protective effect on vascular endothelial function. Zofenoprilat regulates oxidative stress-related molecules, exhibits antioxidant activity[1][2].
Molecular Weight:
325.45
Purity:
97.5
CAS Number:
[75176-37-3]
Formula:
C15H19NO3S2
Target:
Angiotensin-converting Enzyme (ACE)
Application Notes:
MCE Product type: Reference compound
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