AP-1/NF-kappaB activation inhibitor 1 is a potent AP-1 and NF-kappaB mediated transcriptional activation inhibitor (IC50=1 µM), without blocking basal transcription driven by the beta-actin promoter. AP-1/NF-kappaB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells[1].
Molecular Weight:
344.25
Purity:
98.08
CAS Number:
[188936-12-1]
Formula:
C13H11F3N4O4
Target:
NF-kappaB
Application Notes:
MCE Product type: Reference compound
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