Chlorthalidone Impurity G, CAS [[16289-13-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-134043
Supplier Catalog Number:
HY-134043
Alternative Catalog Number:
MCE-HY-134043-1MG,MCE-HY-134043-5MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
Chlorthalidone EP Impurity G
Chlorthalidone Impurity G (Chlorthalidone EP Impurity G) is a potential impurity found in commercial preparations of chlorthalidone with moderate antihypertensive effects. Chlorthalidone is a thiazide diuretic that inhibits the Na+/Cl- cotransporter in the distal tubule of the kidney, thereby preventing sodium and chloride reabsorption, resulting in decreased plasma volume and cardiac output. It also inhibits carbonic anhydrase (CA), including isoenzymes CAVB, VII, IX, XII, and XIII (Kis=2.8-23 nM) and to a lesser extent CAI, CAII, IV, VA, and VI (Ki=138-1,347 nM), mediating vasodilatory activity.
Molecular Weight:
294.13
CAS Number:
[16289-13-7]
Formula:
C14H9Cl2NO2
Target:
Carbonic Anhydrase
Application Notes:
MCE Product type: Reference compound
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