CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade[1][2].
Molecular Weight:
365.89
Purity:
98.02
CAS Number:
[2416095-06-0]
Formula:
C14H20ClNO4S2
Target:
Keap1-Nrf2
Application Notes:
MCE Product type: Reference compound
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