6-T-GDP (6-Thioguanosine 5-diphosphate) is a metabolite of azathioprine. 6-T-GDP can reduce the transcription of inflammatory factors and the expression of cell adhesion molecules by inhibiting the activity of Rac1, thereby inhibiting the migration of leukocytes and the occurrence of tissue inflammation[1].
Molecular Weight:
459.27
CAS Number:
[16541-19-8]
Formula:
C10H15N5O10P2S
Target:
Endogenous Metabolite,Ras
Application Notes:
MCE Product type: Reference compound
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