Deguelin (Standard) is the analytical standard of Deguelin. This product is intended for research and analytical applications. Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-kappaB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1alpha, COX-2, and NF-kappaB.
Molecular Weight:
394.42
Purity:
98.05
CAS Number:
[522-17-8]
Formula:
C23H22O6
Target:
Akt,Apoptosis,Autophagy,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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