cAIMP (Cyclic Adenosine-Inosine Monophosphate) is an effective synthetic cyclic dinucleotide. cAIMP activates IRF and NF-kappaB in the THP1 human monocyte reporter cell line (THP1-Dual). cAIMP induces the secretion of IFNs and pro-inflammatory cytokines in vitro in human blood, with an EC50 of 6.4 µmol/L[1].
Molecular Weight:
659.40
CAS Number:
[1507367-51-2]
Formula:
C20H23N9O13P2
Target:
IFNAR,NF-kappaB
Application Notes:
MCE Product type: Reference compound
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