Bocidelpar (ASP0367, MA-0211) is a selective, orally active PPARdelta modulator. Bocidelpar activates the PPARdelta downstream signaling pathway, upregulates the expression of target genes such as ABCA1 and ACAA2. Bocidelpar then promotes fatty acid oxidation (FAO) and mitochondrial biogenesis, and improves mitochondrial dysfunction. Bocidelpar can improve mitochondrial biogenesis and function in muscle cells. Bocidelpar is mainly used in the study of mitochondrial dysfunction diseases such as primary mitochondrial myopathy (PMM) and Duchenne muscular dystrophy (DMD)[1][2].
Molecular Weight:
460.49
Purity:
98.08
CAS Number:
[2095128-20-2]
Formula:
C25H27F3N2O3
Target:
PPAR
Application Notes:
MCE Product type: Reference compound
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