AMG 511, CAS [[1253573-53-3]]

Product Overview

• Article Name: AMG 511, CAS [[1253573-53-3]]
• Biozol Catalog Number: MCE-HY-13440
• Supplier Catalog Number: HY-13440
• Alternative Catalog Number: MCE-HY-13440-1MG,MCE-HY-13440-10MMX1ML,MCE-HY-13440-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks, with Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3Kalpha, beta, delta and gamma, respectively. AMG 511 significantly suppresses PI3K signaling that is indicated by p-Akt (Ser473) decrease. AMG 511 exhibits anti-tumor activity in mouse glioblastoma xenograft model[1].

Product Properties

• Molecular Weight: 517.58
• Purity: 99.76
• CAS Number: [1253573-53-3]
• Formula: C22H28FN9O3S
• Target: PI3K

Application Notes

• Application Notes: MCE Product type: Reference compound