NHWD-870 is a potent, orally active and selective BET family bromodomain inhibitor and only binds bromodomains of BRD2, BRD3, BRD4 (IC50=2.7 nM), and BRDT. NHWD-870 has potent tumor suppressive efficacies and suppresses cancer cell-macrophage interaction. NHWD-870 increases tumor apoptosis and inhibits tumor proliferation[1].
Molecular Weight:
491.59
Purity:
99.36
CAS Number:
[2115742-03-3]
Formula:
C29H29N7O
Target:
Apoptosis,Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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