(2E)-TCO-PNB ester is an active reaction substrate with the properties of trans-cyclooctene derivatives. The core chemical property of (2E)-TCO-PNB ester is its ability to undergo efficient inverse electron-demand Diels-Alder (IEDDA) cycloaddition with tetrazine groups. (2E)-TCO-PNB ester can be used in ligation reactions to verify the integrity of tetrazine groups, and also serves as a key synthetic raw material for the preparation of the prodrug TCO-DOX. (2E)-TCO-PNB ester is applied in research related to drug synthesis and bioorthogonal chemistry[1][2].
Molecular Weight:
291.30
Purity:
99.69
CAS Number:
[1580501-97-8]
Formula:
C15H17NO5
Target:
Biochemical Assay Reagents
Application Notes:
MCE Product type: Reference compound
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