MD-222 is the first-in-class highly potent PROTAC degrader of MDM2. MD-222 consists of ligands for Cereblon and MDM2. MD-222 induces rapid degradation of the MDM2 protein and activation of wild-type p53 in cells. MD-222 has anticancer effects[1][2].
Molecular Weight:
893.83
Purity:
98.03
CAS Number:
[2136246-72-3]
Formula:
C48H47Cl2FN6O6
Target:
E1/E2/E3 Enzyme,MDM-2/p53,PROTACs
Application Notes:
MCE Product type: Reference compound
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