INCB086550 is a potent, oral, small-molecule PD-L1 inhibitor with IC50s value of 3.1, 4.9 and 1.9 nM for human, cynomolgus, and rat, respectively. INCB086550 promotes the dimerization of cell-surface PD-L1 and induces PD-L1 entry into Golgi vesicles then traffick to the nucleus. INCB086550 can be used for multiple cancers research[1].
Molecular Weight:
693.79
Purity:
99.80
CAS Number:
[2230911-59-6]
Formula:
C41H39N7O4
Target:
PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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