(32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC50s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2)[1].
Molecular Weight:
1776.11
Purity:
95.41
CAS Number:
[2382768-55-8]
Formula:
C93H134N10O24
Target:
mTOR
Application Notes:
MCE Product type: Reference compound
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