HS-243 is a potent and selective IRAK-4 and IRAK-1 inhibitor, with IC50 values of 20 and 24 nM. HS-243 shows minimal TAK1 (transforming growth factor beta-activated kinase 1) inhibition activity, with a IC50 of 0.5 µM. HS-243 shows anti-inflammatory and anticancer activity[1].
Molecular Weight:
324.33
Purity:
99.95
CAS Number:
[848249-10-5]
Formula:
C17H16N4O3
Target:
CDK,IRAK
Application Notes:
MCE Product type: Reference compound
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