CA77.1 is a potent, brain-penetrant and orally active chaperone-mediated autophagy (CMA) activator with favorable pharmacokinetics. CA77.1 is a derivative of AR7 (HY-101106) and can increase the expression of the lysosomal receptor LAMP2A in lysosomes. CA77.1 improves behavior and neuropathology in PS19 mice model and can be used for alzheimers disease research[1].
Molecular Weight:
297.74
Purity:
99.98
CAS Number:
[2412270-22-3]
Formula:
C16H12ClN3O
Target:
Autophagy
Application Notes:
MCE Product type: Reference compound
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