Pyridinium bisretinoid A2E (A2E) TFA is a fluorophore that can be isolated from lipofuscin in the retinal pigment epithelium (RPE). Pyridinium bisretinoid A2E TFA is an initiator of blue-light-induced apoptosis. Photoactivation of Pyridinium bisretinoid A2E TFA mediates autophagy and the production of reactive oxygen species. Pyridinium bisretinoid A2E TFA can be used in the study of retinal degenerative diseases[1][2].
Molecular Weight:
705.93
Purity:
90.00
CAS Number:
[1821308-73-9]
Formula:
C44H58F3NO3
Target:
Apoptosis,Autophagy,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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