JNJ-41443532 (CCR2 antagonist 5) is a selective, orally active hCCR2 inhibitor with good binding affinity (IC50=37 nM) and potent functional antagonism (chemotaxis IC50=30 nM). JNJ-41443532 displays a Ki of 9.6 µM for mCCR2 binding. JNJ-41443532 can be used in the research of inflammatory disease[1].
Molecular Weight:
482.52
Purity:
99.65
CAS Number:
[1228650-83-6]
Formula:
C22H25F3N4O3S
Target:
CCR
Application Notes:
MCE Product type: Reference compound
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