DC4SMe, a phosphate proagent of cytotoxic DNA alkylator DC4, can be used in the synthesis of antibody-drug conjugate (ADC). DC4SMe exhibits IC50s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer[1].
Molecular Weight:
764.21
CAS Number:
[615538-47-1]
Formula:
C35H31ClN5O7PS2
Target:
ADC Payload
Application Notes:
MCE Product type: ADC Related
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