DC44SMe, a phosphate proagent of cytotoxic DNA alkylator DC44, can be used in the synthesis of antibody-drug conjugate (ADC). DC44SMe exhibits IC50s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer[1].
Molecular Weight:
806.29
CAS Number:
[1354787-76-0]
Formula:
C38H37ClN5O7PS2
Target:
ADC Payload
Application Notes:
MCE Product type: ADC Related
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