AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity[1][2][3].
Molecular Weight:
297.30
Purity:
99.59
CAS Number:
[19350-66-4]
Formula:
C14H19NO6
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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