NBDHEX is a potent glutathione S-transferase P1-1 (GSTP1-1) inhibitor. NBDHEX induces apoptosis of tumor cells. NBDHEX acts as an anticancer agent by inhibiting GSTs catalytic activity, avoiding inconvenience of the inhibitor extrusion from the cell by specific pumps and disrupting the interaction between the GSTP1-1 and key signaling effectors. NBDHEX can also act as late-phase autophagy inhibitor[1][2].
Molecular Weight:
297.33
Purity:
98.56
CAS Number:
[787634-60-0]
Formula:
C12H15N3O4S
Target:
Apoptosis,Autophagy,Glutathione S-transferase
Application Notes:
MCE Product type: Reference compound
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