A 131701 is a selective alpha1a- (Ki: 0.22 nM for human alpha1a) and alpha1d-adrenoceptor antagonist. A 131701 antagonizes epinephrine-induced increases in intraurethral pressure (IUP). A 131701 causes transient decreases in mean arterial blood pressure (MABP) and transient tachycardia. A 131701 can be used in the research of spontaneous hypertension[1].
Molecular Weight:
448.54
CAS Number:
[181490-18-6]
Formula:
C24H24N4O3S
Target:
Adrenergic Receptor
Application Notes:
MCE Product type: Reference compound1
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