Lorlatinib (acetate), CAS [[1924207-18-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-135509
Supplier Catalog Number:
HY-135509
Alternative Catalog Number:
MCE-HY-135509-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
PF-06463922 (acetate)
Lorlatinib (PF-06463922) acetate is a selective, orally active, brain-penetrant and ATP-competitive ROS1/ALK inhibitor with anticancer activity. Lorlatinib acetate has Kis of L1196M, respectively. Lorlatinib acetate targets to EML4-ALK, and inhibits ALK phosphorylation with IC50s of 15-43 nM (ALKL1196), 14-80 nM (ALKG1269A), 38-50 nM (ALK1151Tins), 77-113 nM (ALKG1202R), respectively[1][2][3].
