PF-5236216, CAS [[1383376-93-9]] Preis auf Anfrage

Product Overview

• Article Name: PF-5236216, CAS [[1383376-93-9]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-135629
• Supplier Catalog Number: HY-135629
• Alternative Catalog Number: MCE-HY-135629-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PF-5236216 is a brain-penetrant CK1delta/CK1epsilon inhibitor with IC50 values of 8 and 36 nM. PF-5236216 inhibits CK1delta and CK1epsilon-mediated PER3 nuclear translocation. PF-5236216 forms an H-bond with the backbone NH of Leu85, hydrophobic stacking with Met82, and a water-mediated H-bond with Lys38 of CK1delta. PF-5236216 can be used as a tool ligand for CNS PET studies[1].

Product Properties

• Molecular Weight: 322.34
• CAS Number: [1383376-93-9]
• Formula: C18H15FN4O
• Target: Casein Kinase

Application Notes

• Application Notes: MCE Product type: Reference compound