PDE8B-IN-1 is a selective inhibitor of phosphodiesterase 8B (PDE8B) with the activity of enhancing insulin secretion. PDE8B-IN-1 showed good efficacy in high-throughput screening and optimized its ligand efficiency through rapid deconstruction. PDE8B-IN-1 showed high target selectivity and good bioavailability in preclinical development, providing a basis for exploring its potential inhibitory use[1].
Molecular Weight:
346.41
Purity:
99.91
CAS Number:
[1305116-69-1]
Formula:
C14H18N8OS
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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