Poly (I:C):Kanamycin (1:1) (sodium)

Product Overview

• Article Name: Poly (I:C):Kanamycin (1:1) (sodium)
• Biozol Catalog Number: MCE-HY-135748A
• Supplier Catalog Number: HY-135748A
• Alternative Catalog Number: MCE-HY-135748A-5MG,MCE-HY-135748A-10MG,MCE-HY-135748A-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Poly (I:C):Kanamycin (1:1) sodium is an isometric complex of Poly (I:C) (HY-135748) and Kanamycin (HY-16566). Poly(I:C) sodium, a synthetic analog of double-stranded RNA, is a TLR3 and retinoic acid-inducible gene I receptor (RIG-I and b>MDA5) agonist. Poly(I:C) sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses and induce apoptosis in cancer cells[1][2]. Kanamycin is an orally active antibacterial agent (Gram-negative/positive bacteria) that inhibits translocation and causes miscoding by binding to the 70S ribosomal subunit. Kanamycin shows good inhibitory activity against Mycobacterium tuberculosis (susceptible and drug-resistant) and Klebsiella pneumoniae, and can be used in the research of tuberculosis and pneumonia[3][4][5][6].

Product Properties

• Purity: 99
• Formula: C18H36N4O11.(C10H13N4O8P)x.(C9H14N3O8P)x.xNa
• Target: Apoptosis,Toll-like Receptor (TLR)

Application Notes

• Application Notes: MCE Product type: Reference compound