BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor with an IC50 of ~0.2 µM. BMVC inhibits Taq DNA polymerase with an IC50 of ~2.5 µM. BMVC increases the melting temperature of G4 structure of telomere and accelerates telomere length shortening. Anticancer activities[1][2].
Molecular Weight:
657.33
Purity:
98.40
CAS Number:
[627810-06-4]
Formula:
C28H25I2N3
Target:
DNA/RNA Synthesis,G-quadruplex,Telomerase
Application Notes:
MCE Product type: Reference compound
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