iso-ADP ribose TEA is the small-molecule ligand for protein nucleic acid modification, comprising parts of two consecutive ADP-ribosyl units within the PAR chain. iso-ADP ribose TEA specifically binds WWE, FHA and OB-fold domains, enabling PAR-dependent functional responses like ubiquitylation and supporting DNA damage signaling and repair. iso-ADP ribose TEA can be used for cancer research[1].
Molecular Weight:
761.70
Purity:
99.97
Formula:
C27H53N7O14P2
Target:
Poly(ADP-ribose) Glycohydrolase (PARG)
Application Notes:
MCE Product type: Oligonucleotides
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