GNE-1858 is a potent and ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor, with IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA, respectively[1].
Molecular Weight:
428.48
Purity:
99.23
CAS Number:
[2680616-96-8]
Formula:
C21H26F2N8
Target:
MAP4K
Application Notes:
MCE Product type: Reference compound
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