CK2/ERK8-IN-1 is a dual casein kinase 2 (CK2) (Ki of 0.25 µM) and ERK8 (MAPK15, ERK7) inhibitor with IC50s of 0.50 µM. CK2/ERK8-IN-1 also binds to PIM1, HIPK2 (homeodomain-interacting protein kinase 2), and DYRK1A with Kis of 8.65 µM, 15.25 µM, and 11.9 µM, respectively. CK2/ERK8-IN-1 has pro-apoptotic efficacy[1].
Molecular Weight:
534.82
Purity:
99
CAS Number:
[1085822-09-8]
Formula:
C11H9Br4N3O2
Target:
Apoptosis,Casein Kinase,DYRK,ERK,Pim
Application Notes:
MCE Product type: Reference compound
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