Lixumistat (IM156) is a novel biguanide mitochondrial protein complex 1 inhibitor of oxidative phosphorylation (OXPHOS) with anti-tumor activity. Lixumistat regulates OXPHOS to attenuate mitochondrial metabolic reprogramming and inhibit lung fibrosis. Lixumistat also suppresses B-cell activation to alleviate systemic lupus erythematosus[1][5].
Molecular Weight:
315.29
Purity:
99.33
CAS Number:
[1422365-93-2]
Formula:
C13H16F3N5O
Target:
Mitochondrial Metabolism
Application Notes:
MCE Product type: Reference compound
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