N1,N11-Diethylnorspermine, CAS [[121749-39-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-13610
Supplier Catalog Number:
HY-13610
Alternative Catalog Number:
MCE-HY-13610-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
Diethylnorspermine, BENSPM, DENSPM, BE-333
N1,N11-Diethylnorspermine is a synthetic analog of the naturally occurring polyamine spermine, can induce polyamine depletion and inhibit tumor cell growth. N1,N11-Diethylnorspermine activates polyamine catabolism and downregulates mTOR protein. N1,N11-Diethylnorspermine induces the release of cytochrome c from mitochondria, resulting in activation of caspase 3. N1,N11-Diethylnorspermine tetrahydrochloride kills glioblastoma multiforme (GBM) through induction of SSAT (spermidine/spermine N1-acetyltransferase) coupled with H2O2 production[1][2][3][4][5][6].
Molecular Weight:
244.42
CAS Number:
[121749-39-1]
Formula:
C13H32N4
Target:
Caspase,mTOR
Application Notes:
MCE Product type: Reference compound
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