CRBN-6-5-5-VHL, CAS [[2362575-45-7]]

Product Overview

• Article Name: CRBN-6-5-5-VHL, CAS [[2362575-45-7]]
• Biozol Catalog Number: MCE-HY-136262
• Supplier Catalog Number: HY-136262
• Alternative Catalog Number: MCE-HY-136262-50MG,MCE-HY-136262-25MG,MCE-HY-136262-100MG,MCE-HY-136262-5MG,MCE-HY-136262-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

CRBN-6-5-5-VHL is a potent and selective von Hippel-Lindau-based cereblon (CRBN) degrader with a DC50 value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3. (Pink: VHL ligand (HY-125845), Blue: E3 Ligase ligand (HY-10984), Black: linker (HY-403544))[1].

Product Properties

• Molecular Weight: 972.20
• Purity: 99.45
• CAS Number: [2362575-45-7]
• Formula: C51H69N7O10S
• Target: E1/E2/E3 Enzyme,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound