Cbl-b-IN-1 (Example 519) is an inhibitor of Cbl-b, with an IC50 of less than 100 nM. Cbl-b-IN-1 can promote the secretion of cytokines such as IL-2, IFN-gamma, and TNF-alpha, facilitate T cell activation, and enhance the TCR signaling pathway. Cbl-b-IN-1 can be used in research on immunomodulation[1][2].
Molecular Weight:
498.62
Purity:
99.66
CAS Number:
[2368841-84-1]
Formula:
C29H34N6O2
Target:
E1/E2/E3 Enzyme,Interleukin Related
Application Notes:
Reference compound
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