Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy[1].
Molecular Weight:
606.77
Purity:
99.95
CAS Number:
[129453-61-8]
Formula:
C32H47F5O3S
Target:
Apoptosis,Autophagy,Estrogen Receptor/ERR
Application Notes:
MCE Product type: Reference compound
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