CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 µM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 µM in GDP binding assay, respectively. Use as a molecular probe[1].
Molecular Weight:
486.38
Purity:
99.84
CAS Number:
[1222513-26-9]
Formula:
C22H20BrN3O3S
Target:
Ras
Application Notes:
MCE Product type: Reference compound
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