RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences[1][2][3].
Molecular Weight:
334.33
Purity:
99.93
CAS Number:
[48208-26-0]
Formula:
C19H14N2O4
Target:
DNA Methyltransferase
Application Notes:
MCE Product type: Reference compound
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