Daminozide, a plant growth regulator, is a selective inhibitor of the human KDM2/7 histone demethylases, with IC50s of 0.55, 1.5 and 2.1 µM for PHF8, KDM2A, and KIAA1718, respectively. Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested[1][2].
Molecular Weight:
160.17
Purity:
99.79
CAS Number:
[1596-84-5]
Formula:
C6H12N2O3
Target:
Histone Demethylase
Application Notes:
MCE Product type: Natural Products
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