AZ13824374 is a potent and selective ATAD2 bromodomain inhibitor (pIC50 of 6.9 in HCT116 cells). AZ13824374 disrupts chromatin interactions and gene transcription by binding to the acetyl-lysine binding site of the ATAD2 bromodomain. AZ13824374 has anticancer activity against breast cancer[1].
Molecular Weight:
562.68
Purity:
99.22
CAS Number:
[3040082-19-4]
Formula:
C30H39FN8O2
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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