Mocravimod (hydrochloride), CAS [[509088-69-1]]

Product Overview

• Article Name: Mocravimod (hydrochloride), CAS [[509088-69-1]]
• Biozol Catalog Number: MCE-HY-13660
• Supplier Catalog Number: HY-13660
• Alternative Catalog Number: MCE-HY-13660-5MG,MCE-HY-13660-10MG,MCE-HY-13660-25MG,MCE-HY-13660-50MG,MCE-HY-13660-10MMX1ML,MCE-HY-13660-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: KRP-203

Product Description

Mocravimod (hydrochloride) is an orally active sphingosine-1-phosphate receptor (S1PR) modulator that blocks the signal required by T cells to egress from lymph nodes and other lymphoid organs. Mocravimod (hydrochloride) preferentially binds to S1PR1 over S1PR2 and S1PR3 in cardiomyocytes. Mocravimod (hydrochloride) significantly lowered the concentration of reactive oxygen species (ROS), prevented mitochondrial permeability transition pore opening, boosted mitochondrial membrane potential (MMP), and increased phosphorylation of AKT, EKR, GSK-3beta, JAK2, and STAT3. Mocravimod (hydrochloride) retains T cell effector function. Mocravimod (hydrochloride) can be used for the study of acute myelogenous leukemia, diabetes and Myocardial Ischemia-Reperfusion Injury (MIRI)[1][2][3][4].

Product Properties

• Molecular Weight: 480.45
• Purity: 99.99
• CAS Number: [509088-69-1]
• Formula: C24H27Cl2NO3S
• Target: Akt,GSK-3,JAK,LPL Receptor,Reactive Oxygen Species (ROS),STAT

Application Notes

• Application Notes: MCE Product type: Reference compound