Fluocinolone is a potent steroid with highly selective glucocorticoid receptor agonist activity. Fluocinolone stabilizes the blood-retinal barrier by enhancing endothelial tight junctions, inhibiting the VEGF pathway and inflammatory factors. Fluocinolone has high lipophilicity, enabling long-term sustained release in the vitreous. Fluocinolone is used in research related to dermatological diseases, diabetic macular edema, uveitis and oral lichen planus[1][2][3][4].
Molecular Weight:
412.42
Purity:
99.25
CAS Number:
[807-38-5]
Formula:
C21H26F2O6
Target:
Glucocorticoid Receptor
Application Notes:
MCE Product type: Reference compound
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