HMR 1031 is a very late antigen-4 (VLA4, i.e., integrin alpha4beta1) inhibitor, with IC50 values of 0.7 nM and 0.3 nM against VLA-4/VCAM-1 and VLA-4/fibronectin, respectively. HMR 1031 blocks allergen-induced airway responses and airway inflammation in mouse and sheep models. HMR 1031 can be used in asthma-related research[1].
Molecular Weight:
627.74
CAS Number:
[479203-71-9]
Formula:
C35H41N5O6
Target:
Integrin
Application Notes:
MCE Product type: Reference compound
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