INH2BP is a poly(ADP-ribose) polymerase (PARP) inhibitor with antioxidant and anti-apoptotic activities. INH2BP reduces the production of intracellular reactive oxygen species (ROS), modulates the expression of apoptosis-related proteins such as Bax, Bcl-2 and cleaved caspase-3 and enhances cell survival through the activation of the ERK1/2 and p38 MAPK signaling pathways. INH2BP is promising for research of cardiovascular diseases[1].
Molecular Weight:
287.05
CAS Number:
[137881-27-7]
Formula:
C9H6INO2
Target:
Bcl-2 Family,Caspase,ERK,p38 MAPK,PARP,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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