SLM6 is a sangivamycin-like molecule. SLM6 is a CDK9 inhibitor. SLM6 inhibits CDK9/cyclin K and CDK9/cyclin T1 kinase activity with IC50s of 280 nM and 133 nM, respectively. SLM6 also inhibits CDK1/cyclin B and CDK2/ cyclin A with IC50s of less than 300 nM. SLM6 induces apoptosis in multiple myeloma (MM) cells[1].
Molecular Weight:
323.31
CAS Number:
[22242-91-7]
Formula:
C12H17N7O4
Target:
CDK
Application Notes:
MCE Product type: Reference compound
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