Gitoxin is a degradation metabolite of Digitoxin (HY-B1357) and a non-competitive Na+/K+-ATPase inhibitor, with an IC50 of 1.18e-6 M against the porcine high-affinity subtype and an IC50 of 2.85e-5 M against the porcine low-affinity subtype. Gitoxin regulates atrial contractility and rhythmicity. Gitoxin is applicable to research related to congestive heart failure[1][2].
Molecular Weight:
780.94
Purity:
95
CAS Number:
[4562-36-1]
Formula:
C41H64O14
Target:
Na+/K+ ATPase
Application Notes:
MCE Product type: Natural Products
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